CACNB2 | Voltage-dependent L-type calcium channel subunit beta-2
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
CACNB2
Synonyms
CACNLB2 MYSB
Protein Name
Voltage-dependent L-type calcium channel subunit beta-2
UniProt ID
Q08289-2 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000282343
NCBI Gene ID
783
Molecular Weight
73581
Protein Length
660
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cell membrane,Sarcolemma;
Function
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Gene Ontology
GO:0005887; GO:1990454; GO:0098684; GO:0005886; GO:0098793; GO:0005891; GO:0051015; GO:0005262; GO:0008331; GO:0005245; GO:0099635; GO:0070509; GO:0007268; GO:0098912; GO:0086045; GO:0007528; GO:1904879; GO:0051928; GO:1901843; GO:0072659; GO:0086091; GO:1901385; GO:0007601
 
Gene Ontology