GTF3C1 | General transcription factor 3C polypeptide 1
 
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Sequence Viewer
Gene
GTF3C1
Synonyms
-
Protein Name
General transcription factor 3C polypeptide 1
UniProt ID
Q12789 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000348510
NCBI Gene ID
2975
Molecular Weight
238875
Protein Length
2109
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus;
Function
Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element.
Gene Ontology
GO:0016020; GO:0005730; GO:0005654; GO:0005634; GO:1990904; GO:0000127; GO:0001002; GO:0001003; GO:0042791; GO:0009303; GO:0006383; GO:0006384; GO:0009304; GO:0042797