MYBPC3 | Myosin-binding protein C, cardiac-type
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
MYBPC3
Synonyms
-
Protein Name
Myosin-binding protein C, cardiac-type
UniProt ID
Q14896 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000442795
NCBI Gene ID
4607
Molecular Weight
140762
Protein Length
1274
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1gxe)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Gene Ontology
GO:0031672; GO:0014705; GO:0097512; GO:0005829; GO:0031430; GO:0030017; GO:0005863; GO:0005865; GO:0030018; GO:0051015; GO:0001671; GO:0042802; GO:0046872; GO:0051371; GO:0017022; GO:0032036; GO:0008307; GO:0031432; GO:0060048; GO:0048739; GO:0055008; GO:0055003; GO:0007155; GO:0003007; GO:0006936; GO:0030049; GO:0032781; GO:0032971; GO:0006942; GO:0045214; GO:0030241; GO:0030240; GO:0071688; GO:0055010
 
Gene Ontology