ZNF638 | Zinc finger protein 638
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
ZNF638
Synonyms
NP220 ZFML
Protein Name
Zinc finger protein 638
UniProt ID
Q14966 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000264447
NCBI Gene ID
27332
Molecular Weight
220625
Protein Length
1978
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus speckle;
Function
Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1 (By similarity). Binds to cytidine clusters in double-stranded DNA (PubMed:8647861). May also regulate alternative splicing of target genes during adipogenesis (By similarity).
Gene Ontology
GO:0005737; GO:0043231; GO:0016607; GO:0005654; GO:0003690; GO:0003723; GO:0008270; GO:0008380