Protein Name
Plectin
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
531791
Protein Length
4684
Protein Domain
3D Structure
(PDB ID : 1mb8)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cytoplasm,Cytoskeleton,Cell junction,Hemidesmosome;
Function
Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
Gene Ontology
GO:0005903; GO:0043034; GO:0005737; GO:0005829; GO:0070062; GO:0005925; GO:0030056; GO:0045111; GO:0016020; GO:0048471; GO:0005886; GO:0042383; GO:0016528; GO:0003779; GO:0030506; GO:0045296; GO:0003723; GO:0005200; GO:0008307; GO:0005198; GO:0031581; GO:0045104; GO:0042060