Localization
Cytoplasm,Chromosome,Centromere,Kinetochore,Cytoplasm,Cytoskeleton,Spindle,Cleavage furrow,Midbody,Cytoplasm,Cytoskeleton,Cilium axoneme,Cell projection,Cilium,Flagellum;
Function
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830).
Gene Ontology
GO:0005930; GO:0032154; GO:0000777; GO:0005829; GO:0070062; GO:0015630; GO:0030496; GO:0097730; GO:0005634; GO:0031105; GO:0005940; GO:0097227; GO:0005819; GO:0001725; GO:0045296; GO:0005525; GO:0003924; GO:0042802; GO:0032947; GO:0005198; GO:0030154; GO:0060271; GO:0061640; GO:0030336; GO:2000134; GO:0043065; GO:1902857; GO:0051291; GO:0016476; GO:0007283