PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
 
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Sequence Viewer
Gene
PFKFB3
Synonyms
-
Protein Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
UniProt ID
Q16875 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000353712
NCBI Gene ID
5209
Molecular Weight
59609
Protein Length
520
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2axn)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphateATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate + H(+)
Localization
Function
Synthesis and degradation of fructose 2,6-bisphosphate.
Gene Ontology
GO:0005829; GO:0005654; GO:0003873; GO:0005524; GO:0004331; GO:0007420; GO:0006003; GO:0006000; GO:0045821