Localization
Membrane,Basolateral cell membrane,Endoplasmic reticulum membrane,Cell junction,Synapse,Postsynaptic cell membrane,Postsynaptic density,Cell junction,Synapse,Cell membrane,Sarcolemma,Cell junction,Cytoplasm,Apical cell membrane;
Function
Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel (By similarity). May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.
Gene Ontology
GO:0016324; GO:0009925; GO:0016323; GO:0030054; GO:0005829; GO:0030425; GO:0005789; GO:0098978; GO:0005902; GO:0031594; GO:0043005; GO:0033270; GO:0005886; GO:0014069; GO:0098839; GO:0099092; GO:0045211; GO:0042734; GO:0030315; GO:0035255; GO:0019894; GO:0030165; GO:0019902; GO:0008022; GO:0019901; GO:0007015; GO:0007155; GO:0098609; GO:0007268; GO:0030866; GO:0001935; GO:0045197; GO:0045930; GO:0099645; GO:0043268; GO:0043113; GO:0097120; GO:0032880