Gene
Synonyms
Kiaa0720 Syx
Protein Name
Pleckstrin homology domain-containing family G member 5
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
118924
Protein Length
1073
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cytoplasm,Cytoplasm,Perinuclear region,Cell membrane,Cell junction,Cell projection,Lamellipodium;
Function
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
Gene Ontology
GO:0005911; GO:0005737; GO:0030139; GO:0030027; GO:0048471; GO:0005886; GO:0098793; GO:0005089; GO:0035767; GO:0043542; GO:0099575; GO:0035023