NHS | Nance-Horan syndrome protein
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
NHS
Synonyms
-
Protein Name
Nance-Horan syndrome protein
UniProt ID
Q6T4R5 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000369400
NCBI Gene ID
4810
Molecular Weight
179135
Protein Length
1651
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Isoform 1: Apical cell membrane,Cell projection,Lamellipodium,Cell junction,Tight junction,Cell junction,Focal adhesion;Isoform 3: Cytoplasm;
Function
May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development.
Gene Ontology
GO:0016324; GO:0005923; GO:0030054; GO:0005925; GO:0005794; GO:0030027; GO:0016604; GO:0030154; GO:0002088