STRADA | STE20-related kinase adapter protein alpha
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer
Gene
STRADA
Synonyms
LYK5 STRAD
Protein Name
STE20-related kinase adapter protein alpha
UniProt ID
Q7RTN6 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000336655
NCBI Gene ID
92335
Molecular Weight
48369
Protein Length
431
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2wtk)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus,Cytoplasm;
Function
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Gene Ontology
GO:0005737; GO:0005829; GO:0005654; GO:0005634; GO:0005524; GO:0019900; GO:0030295; GO:0043539; GO:0004674; GO:0032147; GO:0007050; GO:0000165; GO:0048812; GO:0006611; GO:0023014; GO:0031098
 
Gene Ontology