Protein Name
Autophagy-related protein 9A
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
94447
Protein Length
839
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cytoplasmic vesicle,Autophagosome membrane,Golgi apparatus,trans-Golgi network membrane,Late endosome membrane,Endoplasmic reticulum membrane;
Function
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
Gene Ontology
GO:0005776; GO:0005789; GO:0005768; GO:0016021; GO:0043231; GO:0005770; GO:0031902; GO:0016020; GO:0000407; GO:0055037; GO:0005802; GO:0000045; GO:0000422; GO:0044805; GO:0034497; GO:0015031