Tph2 | Tryptophan 5-hydroxylase 2
 
Sequence Viewer
Gene
Tph2
Synonyms
Ntph
Protein Name
Tryptophan 5-hydroxylase 2
UniProt ID
Q8CGV2 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSMUSP00000006949
NCBI Gene ID
216343
Molecular Weight
55859
Protein Length
488
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
1.14.16.4; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 5-hydroxy-L-tryptophan
Localization
Function
-
Gene Ontology
GO:0043005; GO:0005506; GO:0004510; GO:0071285; GO:0007623; GO:0014823; GO:0051592; GO:0043627; GO:0051384; GO:0031667; GO:0006587