DAZL | Deleted in azoospermia-like
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
DAZL
Synonyms
DAZH DAZL1 DAZLA SPGYLA
Protein Name
Deleted in azoospermia-like
UniProt ID
Q92904 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000250863
NCBI Gene ID
1618
Molecular Weight
33178
Protein Length
295
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Nucleus;
Function
RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).
Gene Ontology
GO:0005737; GO:0005622; GO:0005634; GO:0032991; GO:0003730; GO:0003723; GO:0008494; GO:0070935; GO:0007281; GO:0007275; GO:0045948; GO:0007283
 
Gene Ontology