FEZ1 | Fasciculation and elongation protein zeta-1
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
Synonyms
-
Protein Name
Fasciculation and elongation protein zeta-1
UniProt ID
Q99689 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
45119
Protein Length
392
Protein Domain
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Catalytic Activity
-
Localization
Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Cell membrane;
Function
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
Gene Ontology
GO:0030424; GO:0005737; GO:0005794; GO:0005874; GO:0005815; GO:0005886; GO:0007411; GO:0007155; GO:1902902; GO:0007399