STRING | IntAct | MINT

Open Targets | OMIM

Catalytic Site Atlas

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Nucleus;

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

GO:0005622; GO:0005634; GO:0090734; GO:0008656; GO:0003700; GO:0000981; GO:0030284; GO:0030331; GO:0042826; GO:0097162; GO:0004879; GO:0043621; GO:0000978; GO:0043565; GO:0008134; GO:0044212; GO:0000976; GO:0006919; GO:0030521; GO:0060442; GO:0048754; GO:0030154; GO:0035690; GO:0071456; GO:0071347; GO:0071383; GO:0071356; GO:0035907; GO:0060664; GO:0007507; GO:0008584; GO:0001656; GO:0071850; GO:0007275; GO:0008285; GO:0050680; GO:0060770; GO:0071899; GO:0010629; GO:0043569; GO:0045930; GO:0045892; GO:0060037; GO:2000836; GO:2001235; GO:0010942; GO:0051781; GO:0008284; GO:0043280; GO:0051091; GO:0010628; GO:2001244; GO:0045931; GO:0014068; GO:0001934; GO:2001022; GO:0045944; GO:0045893; GO:0043491; GO:0032880; GO:0006355; GO:0033574; GO:0007431; GO:0001756