Protein Name
Myb-binding protein 1A
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
148855
Protein Length
1328
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cytoplasm,Nucleus,Nucleus,Nucleolus;
Function
May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309).
Gene Ontology
GO:0005737; GO:0043231; GO:0016020; GO:0042564; GO:0005730; GO:0005654; GO:0005634; GO:0070888; GO:0003723; GO:0043565; GO:0003714; GO:0008134; GO:0042149; GO:0032922; GO:0072332; GO:0045892; GO:0001649; GO:2000210; GO:0071158; GO:0045815; GO:0006355; GO:0022904; GO:0042254