RTKN | Rhotekin
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
RTKN
Synonyms
RTKN1
Protein Name
Rhotekin
UniProt ID
Q9BST9-2 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000233330
NCBI Gene ID
6242
Molecular Weight
62667
Protein Length
563
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
Gene Ontology
GO:0005826; GO:0005829; GO:0005525; GO:0017049; GO:0005095; GO:0000915; GO:0006915; GO:0030865; GO:0000281; GO:1904498; GO:0042981; GO:0007266; GO:0031106; GO:0007165