OSBPL11 | Oxysterol-binding protein-related protein 11
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer
Gene
OSBPL11
Synonyms
ORP11 OSBP12
Protein Name
Oxysterol-binding protein-related protein 11
UniProt ID
Q9BXB4 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000296220
NCBI Gene ID
114885
Molecular Weight
83643
Protein Length
747
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2d9x)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Late endosome membrane,Golgi apparatus,trans-Golgi network membrane;
Function
Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193).
Gene Ontology
GO:0005829; GO:0005794; GO:0043231; GO:0031902; GO:0016020; GO:0005654; GO:0008289; GO:0032934; GO:0015248; GO:0045444; GO:0010890