FANCE | Fanconi anemia group E protein
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
Synonyms
FACE
Protein Name
Fanconi anemia group E protein
UniProt ID
Q9HB96 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
58711
Protein Length
536
Protein Domain
3D Structure
(PDB ID : 2ilr)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Catalytic Activity
-
Localization
Nucleus;
Function
As part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. Required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.
Gene Ontology
GO:0043240; GO:0005654; GO:0005634; GO:0036297