Rims1 | Regulating synaptic membrane exocytosis protein 1
 
Sequence Viewer
Gene
Rims1
Synonyms
Rim1
Protein Name
Regulating synaptic membrane exocytosis protein 1
UniProt ID
Q9JIR4 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
-
NCBI Gene ID
84556
Molecular Weight
179655
Protein Length
1615
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1zub)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cell membrane,Cell junction,Synapse,Cell junction,Synapse,Presynaptic cell membrane;
Function
Rab effector involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity. Plays a role in dendrite formation by melanocytes.
Gene Ontology
GO:0030054; GO:0048788; GO:0098978; GO:0005886; GO:0098831; GO:0042734; GO:0045202; GO:0044325; GO:0046872; GO:0019901; GO:0017137; GO:0017124; GO:0048791; GO:0030154; GO:0006886; GO:0060291; GO:2000463; GO:0010628; GO:0097151; GO:0050806; GO:0031632; GO:0010808; GO:0042391; GO:0048167; GO:2000300
 
Gene Ontology