RRN3 | RNA polymerase I-specific transcription initiation factor RRN3
 
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Sequence Viewer
Gene
RRN3
Synonyms
TIFIA
Protein Name
RNA polymerase I-specific transcription initiation factor RRN3
UniProt ID
Q9NYV6 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000198767
NCBI Gene ID
54700
Molecular Weight
74107
Protein Length
651
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus,Nucleolus;
Function
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity).
Gene Ontology
GO:0005730; GO:0005654; GO:0005634; GO:0001042; GO:0001164; GO:0001181; GO:0008283; GO:0007028; GO:0048872; GO:0001701; GO:1902254; GO:0007000; GO:0010976; GO:0045893; GO:2000142; GO:0042254; GO:0006361
 
Gene Ontology