CaMKinet | Result

Gene

Synonyms

C12orf1

Protein Name

tRNA (guanine-N(7)-)-methyltransferase

UniProt ID

Q9UBP6 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000257848

NCBI Gene ID

Molecular Weight

31471

Protein Length

276

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 3ckk)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

2.1.1.33; (BRENDA)

Catalytic Site

Catalytic Activity

guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine

Localization

Nucleus;

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

Gene Ontology

GO:0005829; GO:0005730; GO:0005654; GO:0005634; GO:0008176; GO:0000049; GO:0036265; GO:0030488; GO:0006400