ING1 | Inhibitor of growth protein 1
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
ING1
Synonyms
-
Protein Name
Inhibitor of growth protein 1
UniProt ID
Q9UK53-2 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000328436
NCBI Gene ID
3621
Molecular Weight
46738
Protein Length
422
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 2qic)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus;
Function
Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
Gene Ontology
GO:0005634; GO:0046872; GO:0035064; GO:0007049; GO:0030308; GO:0008285; GO:0045893; GO:0010941