DDX19B | ATP-dependent RNA helicase DDX19B
 
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Sequence Viewer
Gene
Synonyms
DBP5 DDX19 TDBP
Protein Name
ATP-dependent RNA helicase DDX19B
UniProt ID
Q9UMR2 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
53927
Protein Length
479
Protein Domain
3D Structure
(PDB ID : 3ews)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
3.6.4.13; (BRENDA)
Catalytic Site
Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
Localization
Cytoplasm,Nucleus,Nuclear pore complex,Nucleus membrane;
Function
ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.
Gene Ontology
GO:0005737; GO:0070062; GO:0016020; GO:0005635; GO:0031965; GO:0005643; GO:0005524; GO:0004386; GO:0003723; GO:0006406