Gene
Synonyms
KIAA1248 SYLD
Protein Name
Protein NDRG2
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
40798
Protein Length
371
Protein Domain
3D Structure
(PDB ID : 2xmq)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Localization
Cytoplasm,Cytoplasm,Perinuclear region,Cell projection,Growth cone;
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Gene Ontology
GO:0005737; GO:0005829; GO:0070062; GO:0005794; GO:0030426; GO:0005634; GO:0048471; GO:0030154; GO:0001818; GO:0070373; GO:0048662; GO:0090361; GO:0010574; GO:0007165; GO:0021762; GO:0016055