YBX2 | Y-box-binding protein 2
 
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Sequence Viewer
Gene
YBX2
Synonyms
CSDA3 MSY2
Protein Name
Y-box-binding protein 2
UniProt ID
Q9Y2T7 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000007699
NCBI Gene ID
51087
Molecular Weight
38518
Protein Length
364
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cytoplasm,Nucleus;
Function
Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity).
Gene Ontology
GO:0005737; GO:0001650; GO:0005634; GO:0003677; GO:0000981; GO:0003723; GO:0048599; GO:0120162; GO:0007283; GO:0006366; GO:0009386
 
Gene Ontology