Protein Name
Peptidyl-tRNA hydrolase 2, mitochondrial
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
19194
Protein Length
179
Protein Domain
3D Structure
(PDB ID : 1q7s)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
Catalytic Site
Catalytic Activity
H2O + N-acyl-L-alpha-aminoacyl-tRNA = an N-acyl-L-amino acid + H(+) + tRNA
Localization
Mitochondrion;
Function
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.
Gene Ontology
GO:0005829; GO:0016020; GO:0005739; GO:0004045; GO:0006915; GO:2000811; GO:0010629; GO:2000210