CaMKinet | Result

Gene

KIF3A

Synonyms

KIF3

Protein Name

Kinesin-like protein KIF3A

UniProt ID

Q9Y496 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000368020

NCBI Gene ID

11127

Molecular Weight

80041

Protein Length

699

Protein Domain

InterPro | Pfam

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cytoplasm,Cytoskeleton,Cell projection,Cilium,Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Centriole;

Function

Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitement of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.

Gene Ontology

GO:1904115; GO:0005814; GO:0005813; GO:0097542; GO:0005929; GO:0005829; GO:0070062; GO:0005871; GO:0016939; GO:0005874; GO:0015630; GO:0005524; GO:0008574; GO:0016887; GO:0008017; GO:0003777; GO:0019903; GO:0017137; GO:0030507; GO:0008089; GO:0019886; GO:0007411; GO:0010457; GO:0060271; GO:0035735; GO:0034454; GO:0007018; GO:0006996; GO:0072383; GO:1902414; GO:0015031; GO:0006890