Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAPKAPK2 (P26651) | Homo sapiens | S113 | TELCRTFSESGRCRY | 0.130 | 0.3117 | - | - | - | - | - | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | S184 | HPPVLRQSISFSGLP | 0.952 | 0.6136 | - | - | - | - | - | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | S186 | PVLRQSISFSGLPSG | 0.961 | 0.6322 | TP | certain | - | 72 | 8 | 143 | 55 | | 15944294 | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | S273 | GGLVRTPSVQSLGSD | 0.963 | 0.8013 | - | - | - | - | - | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | S323 | LPIFNRISVSE____ | 0.931 | 0.3774 | - | - | - | - | - | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | S60 | RLPGRSTSLVEGRSC | 0.751 | 0.3807 | TP | certain | experimental | 72 | 8 | 143 | 55 | | 15944294 | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | S66 | TSLVEGRSCGWVPPP | 0.285 | 0.4582 | U | likely | predicted | 14 | | 20221403 | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | T257 | CPSCRRATPISVWGP | 0.223 | 0.2951 | - | - | - | - | - | - | - |
| MAPKAPK2 (P26651) | Homo sapiens | T271 | PLGGLVRTPSVQSLG | 0.060 | 0.562 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Kinase Gene Name" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)