| Parameter | Value |
|---|---|
| Gene | Mybpc3 |
| Protein Name | MYPC3_MOUSE |
| Organism | Mus musculus (Mouse) |
| Alternative name(s) | Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) |
| Protein Family | Immunoglobulin superfamily |
| NCBI Gene ID | N/A |
| UniProt ID | O70468 |
| Enzyme Class | - |
| Molecular Weight | 140632 |
| Protein Length | 1270 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | N/A |
| Function (UniProt annotation) | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. |
| Gene Ontology | GO:0002027; GO:0003007; GO:0005200; GO:0005856; GO:0005863; GO:0005865; GO:0006936; GO:0007155; GO:0008016; GO:0008307; GO:0017022; GO:0030016; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0031034; GO:0031430; GO:0031672; GO:0032036; GO:0042802; GO:0045214; GO:0046872; GO:0048739; GO:0051015; GO:0051371; GO:0055003; GO:0055008; GO:0055010; GO:0060048; GO:0097512 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RPS6KA3 (P51812) | Homo sapiens | S282 | AGAGRRTSDSHEDAG | N/A | N/A | TP | certain | experimental | 148 | 73 | 8 | 55 | 72 | | 21148481 | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S302 | SLLKKRDSFRRDSKL | N/A | 0.391 | - | - | - | - | - | - |
|
| PRKD1 (Q15139) | Homo sapiens | S302 | SLLKKRDSFRRDSKL | N/A | 0.391 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found