CaMKinet | Result

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Sequence Viewer

Parameter	Value
Gene	VIM
Protein Name	VIME_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Vimentin
Protein Family	Intermediate filament family
NCBI Gene ID	7431
UniProt ID	P08670
Enzyme Class	-
Molecular Weight	53652
Protein Length	466
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm
Function (UniProt annotation)	Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
Gene Ontology	GO:0003725; GO:0005200; GO:0005212; GO:0005737; GO:0005777; GO:0005829; GO:0005844; GO:0005856; GO:0005882; GO:0005886; GO:0005925; GO:0008022; GO:0010977; GO:0014002; GO:0016032; GO:0016363; GO:0019221; GO:0019904; GO:0030049; GO:0031252; GO:0032967; GO:0042802; GO:0043005; GO:0043488; GO:0045109; GO:0045335; GO:0045727; GO:0060020; GO:0060395; GO:0070062; GO:0070307; GO:0071222; GO:0071225; GO:0071346; GO:0097110; GO:1990254; GO:1990904

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MAPKAPK2 (P49137)	Homo sapiens	S39	TTSTRTYSLGSALRP	0.934	0.4725	TP	certain	experimental	73 \| 135 \| 55 \| 50 \|	12761892	Non high throughput (12761892)	In vitro
MAPKAPK2 (P49137)	Homo sapiens	S51	LRPSTSRSLYASSPG	0.118	0.4766	TP	certain	experimental	73 \| 135 \| 55 \| 50 \|	12761892	Non high throughput (12761892)	In vitro
MAPKAPK2 (P49137)	Homo sapiens	S56	SRSLYASSPGGVYAT	0.931	0.5533	TP	certain	experimental	73 \| 55 \| 50 \|	12761892	Non high throughput (12761892)	In vitro
MAPKAPK2 (P49137)	Homo sapiens	S83	GVRLLQDSVDFSLAD	0.105	0.2918	TP	certain	experimental	73 \| 55 \| 50 \|	12761892	Non high throughput (12761892)	In vitro
CAMK2A (Q9UQM7)	Homo sapiens	S83	GVRLLQDSVDFSLAD	0.105	0.2918	-	-	-	-	16140754, 9794428	Non high throughput (16140754, 9794428)	In vivo
CAMK2D (Q13557)	Homo sapiens	S83	GVRLLQDSVDFSLAD	0.105	0.2918	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	S39	TTSTRTYSLGSALRP	0.934	0.4725	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	S26	GTASRPSSSRSYVTT	0.396	0.7629	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	S412	EGEESRISLPLPNFS	0.035	0.4292	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	S66	GVYATRSSAVRLRSS	0.166	0.5176	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	S72	SSAVRLRSSVPGVRL	0.756	0.433	-	-	-	-	-	-	-
CAMK2B (Q13554)	Homo sapiens	S39	TTSTRTYSLGSALRP	0.934	0.4725	-	-	-	-	-	-	-
CAMK2D (Q13557)	Homo sapiens	S39	TTSTRTYSLGSALRP	0.934	0.4725	-	-	-	-	-	-	-
CAMK2G (Q13555)	Homo sapiens	S39	TTSTRTYSLGSALRP	0.934	0.4725	-	-	-	-	-	-	-
CAMK2B (Q13554)	Homo sapiens	S83	GVRLLQDSVDFSLAD	0.105	0.2918	-	-	-	-	-	-	-
CAMK2G (Q13555)	Homo sapiens	S83	GVRLLQDSVDFSLAD	0.105	0.2918	-	-	-	-	-	-	-

Interaction Network

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

NCI Nature PID Pathways

Pathway ID	Pathway Name
aurora_b_pathway	Aurora B signaling
caspase_pathway	Caspase cascade in apoptosis