| Gene |
QDPR
|
| Protein Name |
DHPR_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase) (Short chain dehydrogenase/reductase family 33C member 1) |
| Protein Family |
Short-chain dehydrogenases/reductases (SDR) family |
| NCBI Gene ID |
5860
|
| UniProt ID |
P09417
|
| Enzyme Class |
1.5.1.34 |
| Molecular Weight |
25790 |
| Protein Length |
244 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
A 5 |
| Localization |
N/A |
| Function (UniProt annotation) |
The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases. |
| Gene Ontology |
GO:0001889; GO:0004155; GO:0005737; GO:0005829; GO:0006520; GO:0006559; GO:0006729; GO:0009055; GO:0010044; GO:0010288; GO:0033762; GO:0035690; GO:0042803; GO:0043005; GO:0051066; GO:0070062; GO:0070402; GO:0070404 |
