CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	HNRNPA1
Protein Name	ROA1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Protein Family	N/A
NCBI Gene ID	3178
UniProt ID	P09651
Enzyme Class	-
Molecular Weight	38747
Protein Length	372
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus
Function (UniProt annotation)	Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (PubMed:17371836). May bind to specific miRNA hairpins (PubMed:28431233).
Gene Ontology	GO:0000381; GO:0000398; GO:0003697; GO:0003723; GO:0003727; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005737; GO:0006405; GO:0008543; GO:0016020; GO:0016032; GO:0016070; GO:0019904; GO:0032211; GO:0032212; GO:0035198; GO:0036002; GO:0042149; GO:0042802; GO:0051028; GO:0051168; GO:0051170; GO:0061752; GO:0070062; GO:0071013; GO:0098505; GO:1903936; GO:1990904

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MKNK1* (Q9BUB5)	Homo sapiens	S192	EMASASSSQRGRSGS	0.141	0.7331	TP	certain	experimental	72 \| 135 \| 148 \| 73 \| 107 \| 9 \|	16111636	-	-
MKNK1* (Q9BUB5)	Homo sapiens	S362	GGYGGSSSSSSYGSG	0.119	0.6375	TP	certain	experimental	72 \| 30 \| 9 \| 148 \| 73 \| 107 \|	16111636	-	-
MKNK1* (Q9BUB5)	Homo sapiens	S363	GYGGSSSSSSYGSGR	0.046	0.6043	TP	certain	experimental	72 \| 30 \| 9 \| 148 \| 73 \| 107 \|	16111636	-	-
MKNK1* (Q9BUB5)	Homo sapiens	S364	YGGSSSSSSYGSGRR	0.06	0.5854	TP	certain	experimental	72 \| 30 \| 9 \| 148 \| 73 \| 107 \|	16111636	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S192	EMASASSSQRGRSGS	0.141	0.7331	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S362	GGYGGSSSSSSYGSG	0.119	0.6375	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S363	GYGGSSSSSSYGSGR	0.046	0.6043	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa03040	Spliceosome

NCI Nature PID Pathways

Pathway ID	Pathway Name
ar_pathway	Coregulation of Androgen receptor activity