| Gene |
PYGB
|
| Protein Name |
PYGB_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Glycogen phosphorylase, brain form (EC 2.4.1.1) |
| Protein Family |
Glycogen phosphorylase family |
| NCBI Gene ID |
5834
|
| UniProt ID |
P11216
|
| Enzyme Class |
2.4.1.1 |
| Molecular Weight |
96696 |
| Protein Length |
843 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
CATALYTIC ACTIVITY: ((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. |
| Localization |
N/A |
| Function (UniProt annotation) |
Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852). Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228). Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228). However, all known phosphorylases share catalytic and structural properties (PubMed:3346228). |
| Gene Ontology |
GO:0005576; GO:0005737; GO:0005980; GO:0008184; GO:0016020; GO:0030170; GO:0035578; GO:0043312; GO:0070062; GO:0102250; GO:0102499 |
