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| Parameter | Value |
|---|---|
| Gene | GFAP |
| Protein Name | GFAP_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Glial fibrillary acidic protein (GFAP) |
| Protein Family | Intermediate filament family |
| NCBI Gene ID | 2670 |
| UniProt ID | P14136 |
| Enzyme Class | - |
| Molecular Weight | 49880 |
| Protein Length | 432 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cytoplasm Note=Associated with intermediate filaments. |
| Function (UniProt annotation) | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| Gene Ontology | GO:0005178; GO:0005200; GO:0005737; GO:0005829; GO:0005882; GO:0009611; GO:0010625; GO:0010977; GO:0014002; GO:0019900; GO:0030198; GO:0031102; GO:0042802; GO:0043209; GO:0043254; GO:0044297; GO:0045109; GO:0051580; GO:0060020; GO:0060291; GO:0097450; GO:0098574; GO:1904714 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK2A (Q9UQM7) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
| CAMK2B (Q13554) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
| CAMK2D (Q13557) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
| CAMK2G (Q13555) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
| CAMK2B (Q13554) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
| CAMK2D (Q13557) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
| CAMK2G (Q13555) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
| CAMK2B (Q13554) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
| CAMK2D (Q13557) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
| CAMK2G (Q13555) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found