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Parameter | Value |
---|---|
Gene | GFAP |
Protein Name | GFAP_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Glial fibrillary acidic protein (GFAP) |
Protein Family | Intermediate filament family |
NCBI Gene ID | 2670 |
UniProt ID | P14136 |
Enzyme Class | - |
Molecular Weight | 49880 |
Protein Length | 432 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cytoplasm Note=Associated with intermediate filaments. |
Function (UniProt annotation) | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
Gene Ontology | GO:0005178; GO:0005200; GO:0005737; GO:0005829; GO:0005882; GO:0009611; GO:0010625; GO:0010977; GO:0014002; GO:0019900; GO:0030198; GO:0031102; GO:0042802; GO:0043209; GO:0043254; GO:0044297; GO:0045109; GO:0051580; GO:0060020; GO:0060291; GO:0097450; GO:0098574; GO:1904714 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CAMK2A (Q9UQM7) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
CAMK2B (Q13554) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
CAMK2D (Q13557) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
CAMK2G (Q13555) | Homo sapiens | S38 | LGPGTRLSLARMPPP | 0.368 | 0.6948 | - | - | - | - | - | - |
|
CAMK2A (Q9UQM7) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
CAMK2B (Q13554) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
CAMK2D (Q13557) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
CAMK2G (Q13555) | Homo sapiens | S13 | ITSAARRSYVSSGEM | 0.795 | 0.4369 | - | - | - | - | - | - |
|
CAMK2A (Q9UQM7) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
CAMK2B (Q13554) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
CAMK2D (Q13557) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
CAMK2G (Q13555) | Homo sapiens | S17 | ARRSYVSSGEMMVGG | 0.894 | 0.4507 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found