| Gene |
STMN1
|
| Protein Name |
STMN1_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Prosolin) (Protein Pr22) (pp17) |
| Protein Family |
Stathmin family |
| NCBI Gene ID |
3925
|
| UniProt ID |
P16949
|
| Enzyme Class |
- |
| Molecular Weight |
17303 |
| Protein Length |
149 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, cytoskeleton. |
| Function (UniProt annotation) |
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity). |
| Gene Ontology |
GO:0000281; GO:0005622; GO:0005737; GO:0005829; GO:0005874; GO:0007019; GO:0007052; GO:0007165; GO:0007409; GO:0007420; GO:0009615; GO:0015631; GO:0016020; GO:0031110; GO:0031115; GO:0031175; GO:0035024; GO:0035556; GO:0043005; GO:0048012; GO:0051272; GO:0051493; GO:0051497; GO:0061436; GO:0070062; GO:0070495; GO:1905098 |
