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| Parameter | Value |
|---|---|
| Gene | PHKA1 |
| Protein Name | KPB1_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit) |
| Protein Family | Phosphorylase b kinase regulatory chain family |
| NCBI Gene ID | 5255 |
| UniProt ID | P46020 |
| Enzyme Class | - |
| Molecular Weight | 137312 |
| Protein Length | 1223 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cell membrane |
| Function (UniProt annotation) | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. |
| Gene Ontology | GO:0004689; GO:0005516; GO:0005829; GO:0005886; GO:0005964; GO:0005977; GO:0006091 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PHKG1 (Q16816) | Homo sapiens | S985 | SNVSPAISIHEIGAV | 0.127 | 0.4441 | - | - | - | - | - | - |
|
| PHKG2 (P15735) | Homo sapiens | S985 | SNVSPAISIHEIGAV | 0.127 | 0.4441 | - | - | - | - | - | - |
|
| PHKG1 (Q16816) | Homo sapiens | S1007 | TGIMQLKSEIKQVEF | 0.746 | 0.3667 | - | - | - | - | - | - |
|
| PHKG2 (P15735) | Homo sapiens | S1007 | TGIMQLKSEIKQVEF | 0.746 | 0.3667 | - | - | - | - | - | - |
|
| PHKG1 (Q16816) | Homo sapiens | S972 | KEFGVERSVRPTDSN | 0.264 | 0.562 | - | - | - | - | - | - |
|
| PHKG2 (P15735) | Homo sapiens | S972 | KEFGVERSVRPTDSN | 0.264 | 0.562 | - | - | - | - | - | - |
|
| PHKG1 (Q16816) | Homo sapiens | S1018 | QVEFRRLSISAESQS | 0.358 | 0.4619 | - | - | - | - | - | - |
|
| PHKG2 (P15735) | Homo sapiens | S1018 | QVEFRRLSISAESQS | 0.358 | 0.4619 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found