CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	RPS6
Protein Name	RS6_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	40S ribosomal protein S6 (Phosphoprotein NP33) (Small ribosomal subunit protein eS6)
Protein Family	Eukaryotic ribosomal protein eS6 family
NCBI Gene ID	6194
UniProt ID	P62753
Enzyme Class	-
Molecular Weight	28681
Protein Length	249
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	N/A
Function (UniProt annotation)	May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
Gene Ontology	GO:0000082; GO:0000184; GO:0001890; GO:0002309; GO:0003723; GO:0003735; GO:0005634; GO:0005654; GO:0005730; GO:0005783; GO:0005829; GO:0005844; GO:0006364; GO:0006412; GO:0006413; GO:0006614; GO:0006924; GO:0007093; GO:0007369; GO:0015935; GO:0016020; GO:0019901; GO:0022605; GO:0022627; GO:0030425; GO:0031929; GO:0033077; GO:0036464; GO:0042274; GO:0042593; GO:0043065; GO:0043066; GO:0044297; GO:0048471; GO:0048821; GO:1990904

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
RPS6KA3 (P51812)	Homo sapiens	S235	IAKRRRLSSLRASTS	0.272	0.708	TP	certain	experimental	148 \| 28 \| 140 \| 72 \| 73 \| 55 \| 8 \|	17360704	-	In vitro
RPS6KA3 (P51812)	Homo sapiens	S236	AKRRRLSSLRASTSK	0.934	0.6991	TP	certain	experimental	148 \| 28 \| 140 \| 72 \| 73 \| 55 \| 8 \|	17360704	-	In vitro
DAPK1 (P53355)	Homo sapiens	S235	IAKRRRLSSLRASTS	0.272	0.708	TP	likely	-	72 \| 73 \| 55 \| 148 \|	18974095	-	-
RPS6KA1 (Q15418)	Homo sapiens	S235	IAKRRRLSSLRASTS	0.272	0.708	-	-	-	-	-	-	In vitro
RPS6KA1 (Q15418)	Homo sapiens	S236	AKRRRLSSLRASTSK	0.934	0.6991	-	-	-	-	-	-	In vitro
PASK (Q96RG2)	Homo sapiens	S235	IAKRRRLSSLRASTS	0.272	0.708	-	-	-	-	-	-	-
PASK (Q96RG2)	Homo sapiens	S236	AKRRRLSSLRASTSK	0.934	0.6991	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

NCI Nature PID Pathways

Pathway ID	Pathway Name
il2_pi3kpathway	IL2 signaling events mediated by PI3K
mtor_4pathway	mTOR signaling pathway