CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	Hist1h3a; Hist1h3g; Hist1h3h; Hist1h3i
Protein Name	H31_MOUSE
Organism	Mus musculus (Mouse)
Alternative name(s)	Histone H3.1
Protein Family	Histone H3 family
NCBI Gene ID	3.19E+22
UniProt ID	P68433
Enzyme Class	-
Molecular Weight	15404
Protein Length	136
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus. Chromosome.
Function (UniProt annotation)	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene Ontology	GO:0000228; GO:0000786; GO:0000788; GO:0005634; GO:0005654; GO:0006334; GO:0006335; GO:0031492; GO:0032991; GO:0046982; GO:0051290; GO:0060968

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
RPS6KA5 (O75582)	Homo sapiens	S11	TKQTARKSTGGKAPR	N/A	0.7595	-	-	-	-	-	-	In vivo
RPS6KA5 (O75582)	Homo sapiens	S29	ATKAARKSAPATGGV	N/A	0.6482	-	-	-	-	-	-	In vivo
CHEK1 (O14757)	Homo sapiens	S11	TKQTARKSTGGKAPR	N/A	0.7595	-	-	-	-	-	-	in-vitro
RPS6KA4 (O75676)	Homo sapiens	S11	TKQTARKSTGGKAPR	N/A	0.7595	-	-	-	-	-	-	in-vitro
CHEK1 (O14757)	Homo sapiens	T12	KQTARKSTGGKAPRK	N/A	0.7505	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
mmu05322	Systemic lupus erythematosus
mmu05322	Systemic lupus erythematosus
mmu05322	Systemic lupus erythematosus
mmu05322	Systemic lupus erythematosus

No NCI Nature pathways found