Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | FOXM1 |
Protein Name | FOXM1_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells) |
Protein Family | N/A |
NCBI Gene ID | 2305 |
UniProt ID | Q08050 |
Enzyme Class | - |
Molecular Weight | 84283 |
Protein Length | 763 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Nucleus. |
Function (UniProt annotation) | Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. |
Gene Ontology | GO:0000086; GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0001558; GO:0003677; GO:0003700; GO:0005654; GO:0006281; GO:0006366; GO:0006978; GO:0008284; GO:0019901; GO:0032873; GO:0042127; GO:0045892; GO:0045893; GO:0045944; GO:0046578; GO:0051726; GO:0071156; GO:0090344; GO:2000377; GO:2000781 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CHEK2 (O96017) | Homo sapiens | S376 | PLLPRVSSYLVPIQF | 0.844 | 0.2193 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
NCI Nature PID Pathways
Pathway ID | Pathway Name |
---|---|
foxm1pathway | FOXM1 transcription factor network |