CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	VPS72
Protein Name	VPS72_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1)
Protein Family	VPS72/YL1 family
NCBI Gene ID	6944
UniProt ID	Q15906
Enzyme Class	-
Molecular Weight	40594
Protein Length	364
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus
Function (UniProt annotation)	Deposition-and-exchange histone chaperone specific for H2AFZ, specifically chaperones H2AFZ and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AFZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.
Gene Ontology	GO:0000122; GO:0003677; GO:0005634; GO:0005654; GO:0016607; GO:0032991; GO:0035019; GO:0042393; GO:0043486

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2A (Q9UQM7)	Homo sapiens	T86	RRKRRVVTKAYKEPL	0.905	0.6227	-	-	-	-	-	-	-
CAMK2B (Q13554)	Homo sapiens	T86	RRKRRVVTKAYKEPL	0.905	0.6227	-	-	-	-	-	-	-
CAMK2D (Q13557)	Homo sapiens	T86	RRKRRVVTKAYKEPL	0.905	0.6227	-	-	-	-	-	-	-
CAMK2G (Q13555)	Homo sapiens	T86	RRKRRVVTKAYKEPL	0.905	0.6227	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	T137	RKSMRQSTAEHTRQT	0.99	0.7799	-	-	-	-	-	-	-
CAMK2B (Q13554)	Homo sapiens	T137	RKSMRQSTAEHTRQT	0.99	0.7799	-	-	-	-	-	-	-
CAMK2D (Q13557)	Homo sapiens	T137	RKSMRQSTAEHTRQT	0.99	0.7799	-	-	-	-	-	-	-
CAMK2G (Q13555)	Homo sapiens	T137	RKSMRQSTAEHTRQT	0.99	0.7799	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	T168	PHCERPLTQEELLRE	0.927	0.6531	-	-	-	-	-	-	-
CAMK2B (Q13554)	Homo sapiens	T168	PHCERPLTQEELLRE	0.927	0.6531	-	-	-	-	-	-	-
CAMK2D (Q13557)	Homo sapiens	T168	PHCERPLTQEELLRE	0.927	0.6531	-	-	-	-	-	-	-
CAMK2G (Q13555)	Homo sapiens	T168	PHCERPLTQEELLRE	0.927	0.6531	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found