CaMKinet | Result

Gene

PRKD3

Synonyms

EPK2 PRKCN

Protein Name

Serine/threonine-protein kinase D3

UniProt ID

O94806 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000234179

NCBI Gene ID

23683

Molecular Weight

100471

Protein Length

890

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 2d9z)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

2.7.11.13; (BRENDA)

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Localization

Cytoplasm,Membrane;

Function

Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).

Gene Ontology

GO:0005829; GO:0016020; GO:0005654; GO:0005524; GO:0016301; GO:0046872; GO:0004697; GO:0004674; GO:0007205; GO:0089700; GO:0006468; GO:0030148