Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HDAC5 * (Q9UQL6 ) | Homo sapiens | S498 | RPLSRTQSSPLPQSP | 0.940 | 0.9126 | TP | certain | not annotated | 140 | 148 | 152 | 8 | | 18332134 | - |
|
| PRKD1 * (Q15139 ) | Homo sapiens | S738 | ARIIGEKSFRRSVVG | 0.590 | 0.0817 | TP | certain | experimental | 23 | 55 | 73 | 140 | | 15024053 | - |
|
| PRKD1 * (Q15139 ) | Homo sapiens | S742 | GEKSFRRSVVGTPAY | 0.714 | 0.1323 | TP | certain | experimental | 23 | 55 | 73 | 140 | | 15024053 | - |
|
| GIT1 (Q9Y2X7) | Homo sapiens | S46 | RSLGRHISIVKHLRH | 0.866 | 0.2645 | - | - | - | - | - | - |
|
| GSK3A (P49840) | Homo sapiens | S21 | SGRARTSSFAEPGGG | 0.000 | 0.919 | - | - | - | - | - | - | - |
| GSK3B (P49841) | Homo sapiens | S9 | SGRPRTTSFAESCKP | 0.500 | 0.5951 | - | - | - | - | - | - | - |
| RTKN (Q9BST9) | Homo sapiens | S448 | QALAKQGSLYHEMAI | 0.952 | 0.4979 | - | - | - | - | - | - | - |
| SPHK2 (Q9NRA0) | Homo sapiens | S419 | AHSPLHRSVSDLPLP | 0.402 | 0.6712 | - | - | - | - | - | - | - |
| SPHK2 (Q9NRA0) | Homo sapiens | S421 | SPLHRSVSDLPLPLP | 0.657 | 0.5992 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)