Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EP300 * (Q09472 ) | Homo sapiens | S24 | KLSSPALSASASDGT | 0.267 | 0.6991 | - | - | - | 205 | 135 | 8 | | 12590608 | - | - |
| Syn1 (P09951) | Rattus norvegicus | S9 | NYLRRRLSDSNFMAN | - | 0.5139 | TP | likely | experimental | 55 | 148 | | 28698220 | - | - |
| Nos1 (P29476-1) | Rattus norvegicus | S847 | SYKVRFNSVSSYSDS | - | 0.3356 | TP | certain | experimental | 72 | 73 | 20 | 8 | 55 | | 10400690 | - | - |
| NUMB (P49757) | Homo sapiens | S276 | EQLARQGSFRGFPAL | 0.857 | 0.5577 | U | likely | experimental | 72 | 55 | | 16105844 | - | - |
| Numbl (Q3MUI2) | Rattus norvegicus | S304 | EQLVRQGSFRGFPAL | - | 0.5707 | U | likely | experimental | 72 | 55 | | 16105844 | - | - |
| Snf1lk2 (Q3LRT3) | Rattus norvegicus | T484 | RSGQRRHTLSEVTNQ | - | 0.6531 | TP | certain | experimental | 72 | 55 | 8 | | 21220102 | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)