Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ppargc1a (O70343) | Mus musculus | S538 | SLFDVSPSCSSFNSP | - | 0.3087 | TP | certain | experimental | 23 | 30 | 9 | 72 | 73 | | 17609368 | - | - |
| NOS3 (P29474) | Homo sapiens | S1177 | TSRIRTQSFSLQERQ | 0.140 | 0.433 | TP | certain | experimental | 30 | 55 | 23 | 135 | | 10025949 | - | - |
| EP300 (Q09472) | Homo sapiens | S89 | SELLRSGSSPNLNMG | 0.391 | 0.6851 | TP | certain | experimental | 72 | 73 | 55 | 9 | | 11518699 | - | - |
| Ppargc1a (O70343) | Mus musculus | T177 | NHTHRIRTNPAIVKT | - | 0.805 | TP | certain | experimental | 23 | 30 | 9 | 72 | 73 | | 17609368 | - | - |
| NOS3 (P29474) | Homo sapiens | T495 | TGITRKKTFKEVANA | 0.231 | 0.3019 | TP | certain | experimental | 30 | 55 | 23 | 135 | | 10025949 | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)