EIF4G3 | Eukaryotic translation initiation factor 4 gamma 3
 
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Sequence Viewer
Gene
EIF4G3
Synonyms
-
Protein Name
Eukaryotic translation initiation factor 4 gamma 3
UniProt ID
O43432 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000264211
NCBI Gene ID
8672
Molecular Weight
176652
Protein Length
1585
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1hu3)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1.
Gene Ontology
GO:0005829; GO:0016281; GO:0003729; GO:0003723; GO:0000339; GO:0008135; GO:0003743; GO:0006446