MBP | Myelin basic protein
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
MBP
Synonyms
-
Protein Name
Myelin basic protein
UniProt ID
P02687 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
-
NCBI Gene ID
Molecular Weight
18323
Protein Length
169
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Myelin membrane;
Function
Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
Gene Ontology
GO:0071944; GO:0043218; GO:0033269; GO:0043209; GO:0043025; GO:0005886; GO:0032991; GO:0005516; GO:0005543; GO:0019911; GO:0042552