TH | Tyrosine 3-monooxygenase
 
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Sequence Viewer
Gene
Synonyms
TYH
Protein Name
Tyrosine 3-monooxygenase
UniProt ID
P07101-4 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
58600
Protein Length
528
Protein Domain
3D Structure
(PDB ID : 2xsn)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
1.14.16.2; (BRENDA)
Catalytic Site
Catalytic Activity
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa
Localization
Function
Plays an important role in the physiology of adrenergic neurons.
Gene Ontology
GO:0030424; GO:0005737; GO:0009898; GO:0031410; GO:0005829; GO:0030425; GO:0033162; GO:0005739; GO:0043005; GO:0005634; GO:0043204; GO:0005790; GO:0008021; GO:0043195; GO:0016597; GO:0035240; GO:0019899; GO:0008199; GO:0008198; GO:0019825; GO:0019904; GO:0034617; GO:0004511; GO:0015842; GO:0009653; GO:0009887; GO:0042423; GO:0071312; GO:0071333; GO:0071363; GO:0071287; GO:0071316; GO:0021987; GO:0042745; GO:0042416; GO:0006585; GO:0042755; GO:0048596; GO:0042418; GO:0042462; GO:0006631; GO:0016137; GO:0007507; GO:0003007; GO:0033076; GO:0007612; GO:0007626; GO:0007617; GO:0007613; GO:0010259; GO:0042136; GO:0042421; GO:0018963; GO:0052314; GO:0043473; GO:0008016; GO:0014823; GO:0001975; GO:0051412; GO:0051602; GO:0032355; GO:0045471; GO:0045472; GO:0009635; GO:0001666; GO:0035902; GO:0035900; GO:0009416; GO:0032496; GO:0031667; GO:0043434; GO:0046684; GO:0009651; GO:0009414; GO:0010043; GO:0007605; GO:0035176; GO:0006665; GO:0001963; GO:0042214; GO:0007601
 
Gene Ontology