VIM | Vimentin
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
Synonyms
-
Protein Name
Vimentin
UniProt ID
P08670 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
53652
Protein Length
466
Protein Domain
3D Structure
(PDB ID : 1gk4)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Catalytic Activity
-
Localization
Cytoplasm,Cytoplasm,Cytoskeleton,Nucleus matrix;
Function
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
Gene Ontology
GO:0031252; GO:0005737; GO:0005856; GO:0005829; GO:0070062; GO:0005925; GO:0005882; GO:0043005; GO:0016363; GO:0005777; GO:0045335; GO:0005886; GO:0005844; GO:1990904; GO:0003725; GO:0042802; GO:1990254; GO:0008022; GO:0019904; GO:0097110; GO:0005200; GO:0005212; GO:0014002; GO:0060020; GO:0071346; GO:0071222; GO:0071225; GO:0019221; GO:0045109; GO:0070307; GO:0030049; GO:0010977; GO:0032967; GO:0045727; GO:0043488; GO:0060395; GO:0016032
 
Gene Ontology